Akina
Polymer University

Polymer University

This is the start of a series of videos covering polymers: What they are, what they can do, and how they are being used in medical, drug delivery, and cancer research.

Polymer 101: What is a Polymer?

 

Polymer 102: Biodegradation

Introduction to polyester degradation, chemistry and rate-controlling factors.

 

Polymer 103: Micelles

Introduction to hydrophobicity, hydrophilicity, interfacial tension, and micelle formation.

 

Polymer 104: Microparticles and Nanoparticles

Introduction to applying polymer medicinal-delivery systems as microparticles and nanoparticles for controlled release.

 

Polymer 105: Thermogels

Educational video on biodegradable thermogelling polymers with focus on PLGA-PEG-PLGA block copolymer.

 

White Papers

Paper Catalog Link
AI147 Photocrosslinking applicationPDFAI147—Stearate-modified methylcellulose acrylate
Blog video: strength and elasticityAP015—Poly(L-lactide-co-caprolactone) LA:CL 50:50
(Mn 75,000-85,000 Da) L
Blog video: Thermogel InjectabilityAK036—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~750:2,500 Da)
Research: Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer TherapyPDFAK010—Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~5,000:10,000 Da)
Storage stability of PLCL-PEG-PLCL thermogel as aqueous solutionPDFAK109—Poly(lactide-co-caprolactone)-b-Poly(ethylene glycol)-b-Poly(lactide-co-caprolactone) (~1700-1500-1700 Da, 60:40 CL:LA)
Testing effects of additives on thermogel dissolution.PDFAK109—Poly(lactide-co-caprolactone)-b-Poly(ethylene glycol)-b-Poly(lactide-co-caprolactone) (~1700-1500-1700 Da, 60:40 CL:LA)
White Paper: Melting point data on select PolyVivo PLA and PLGA polymersPDFAP003—Poly(D,L-lactide) ester endcap
(Mn 45,000-55,000 Da) DL
AP004—Poly(D,L-lactide) ester endcap
(Mn 65,000-75,000 Da) DL
AP005—Poly(D,L-lactide) acid endcap
(Mn 1,000-5,000 Da) DL
AP016—Poly(lactide-co-glycolide) LG 60:40
acid endcap
(Mn 15,000-25,000 Da)
AP020—Poly(lactide-co-glycolide) LG 85:15
acid endcap
(Mn 100,000-125,000 Da)
AP024—Poly(lactide-co-glycolide) LG 85:15
ester endcap
(Mn 35,000-45,000 Da)
AP030—Poly(lactide-co-glycolide) LG 85:15
ester endcap
(Mn 10,000-15,000 Da)
AP031—Poly(lactide-co-glycolide) LG 85:15
ester endcap
(Mn 25,000-35,000 Da)
AP112—Poly(lactide-co-glycolide)-dialcohol endcap LG 50:50
butanediol initiated
(Mn 1,000-5,000 Da)
White Paper: Passive dissolution of Coumarin-6 into water by PolyVivoPDFAK009—Methoxy poly(ethylene glycol)-b-poly(D,L-lactide) (Mw ~2,000:2,200 Da)
AK009D—Poly(ethylene glycol)-b-poly(D,L-lactic acid)-decyl (Mw ~2,000:2,200 Da)
AK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
AK019—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~1,500:1,500:1,500 Da)
AK023—Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~2,000:1,500 Da)
AK024—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 75:25 (w:w)
(Mn ~1,100:1,000:1,100 Da)
AK030—Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~5,000:4,000 Da)
AK035—Poly(caprolactone)-b-poly(ethylene glycol)-b-poly(caprolactone) (Mw ~1,000:1,000:1,000 Da)
AK036—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~750:2,500 Da)
AK046—Poly(D,L-lactide)-b-poly(ethylene glycol)-b-poly(D,L-lactide) (Mw ~1,000:1,000:1,000 Da)
AK047—Methoxy poly(ethylene glycol)-b-poly(L-lactide) (Mw ~5,000:1,000 Da)
AK048—Methoxy poly(ethylene glycol)-b-poly(L-lactide) (Mw ~5,000:500 Da)
AO004—Poly(sulfopropyl acrylate) (Viscosity = 10-100 cP; 1% in water at 60 RPM)
AO014—Poly(N-isopropylacrylamide-co-acrylic acid) 95:5 NIPAM:AA
AO016—Poly(N-isopropylacrylamide-co-acrylamide) 50:50 NIPAM:AM
AO017—Poly(N-isopropylacrylamide-co-methoxy poly(ethylene glycol) methacrylate) 95:5 NIPAM:mPEG
(Mn 475 Da)
AO018—Poly(vinylcaprolactam-co-methoxy poly(ethylene glycol) methacrylate) 95:5 VCL:mPEG
AO019—Poly(dimethylaminoethyl methacrylate-co-methoxy poly(ethylene glycol)) 95:5 DMAEMA:mPEG
AO020—Poly(Poloxamer 407)-co-hexamethylene-diisocyanate copolymer methoxy poly(ethylene glycol) 10:1 PF:mPEG
nominal 10 poloxamer chains/mPEG endcap
(5,000 Da)
AO021—Poly(N-isopropylacrylamide-co-acrylamide) 75:25 NIPAM:AM
AO023—Poly(N-isopropylacrylamide-co-acrylamide) 95:5 NIPAM:AM
AO026—Poly(Poloxamer 407)-methylene-diphenyl-di-isocyanate linked
AO031—Poly(N-vinylcaprolactam)
White Paper: Thermogel Mixtures impact on RheologyPDFAK019—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~1,500:1,500:1,500 Da)
WhitePaper: AI057 viscosity in waterPDFAI057—Poly(N-isopropylacrylamide)-N-hydroxysuccinimide endcap (Inherent viscosity (I.V.) = 0.2-0.5 dL/g in methanol at 25°C)
WhitePaper: AO23 cold viscosityPDFAO023—Poly(N-isopropylacrylamide-co-acrylamide) 95:5 NIPAM:AM
WhitePaper: In-vivo imaging with PolyVivo AV006 (PLGA-FPI749)PDFAV006—Poly(lactide-co-glycolide)-FPI749 LG 50:50
FPI749 endcap
Flamma Fluor near-IR conjugated
(Mn 20,000-30,000 Da) (nominal 2mg/G labeling)
WhitePaper: PolyVivo AO19 pH and temperature sensitivePDFAO019—Poly(dimethylaminoethyl methacrylate-co-methoxy poly(ethylene glycol)) 95:5 DMAEMA:mPEG
WhitePaper: Sensitive to both pH and temperaturePDFAO014—Poly(N-isopropylacrylamide-co-acrylic acid) 95:5 NIPAM:AA
WhitePaper: Solubilization of a drug (AK09D)PDFAK009D—Poly(ethylene glycol)-b-poly(D,L-lactic acid)-decyl (Mw ~2,000:2,200 Da)
WhitePaper: Thermal properties mPEG-PCL polymersPDFAK001—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~2,000:5,200 Da)
WhitePaper: Thermogel speed of mixed PolyVivo AK019 and AK012PDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
WhitePaper: Thermogel Users GuidePDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
WhitePaper: Thermogels mixed with biocomponents for 3D cell scaffoldPDFAO025—Stearate-modified methyl cellulose Hydrophobically modified thermogel
AO026—Poly(Poloxamer 407)-methylene-diphenyl-di-isocyanate linked
WhitePaper: Thermosensitive nanoparticles AO034 loaded with Coumarin-6PDFAO034—Poly(N-vinylcaprolactam-co-methylmethacrylate) 90:10 VCL:MMA
(Inherent Viscosity (I.V.) = 0.3-0.7 dL/g in ethanol at 30° C)
WhitePaper: Using AK01 to form poorly soluble drug loaded liposomesPDFAK001—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~2,000:5,200 Da)
WhitePaper: Viscosity and Thermal Properties (AK12)PDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
 

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